TUYCHIBOEVA M.N., MURADOV A.M. SHUKUROV T., SHUMILINA O.V.
COURSE “LABORATORY WORK” TIPGPMP
One of the most urgent problems in the structure of modern somatic pathology remains endo¬toxicosis, which is a basic component of the formation of the severity of the General condition. The article presents the results of analysis of toxic blood components 206 patients endotoxemia developed in the result of acute renal failure, peritonitis and septicemia in comparison with the figures of 20 healthy donors. Material for the study served as the blood of patients aged from 17 to 62 years, of which men made up 59,3% of women – 40,3%. The study used biochemical, gel-chromatography and infrared spectroscopic methods of diagnostics indicators token to reflect the level of intoxication. Found that the toxicity index in patients endotoxemia increases by more than 700%, compared with the control. On the basis of carried out research we can conclude that the patients endotoxemia occur intensification of lipid peroxidation, depression of immunity, reduction in antioxidant protection and detoxification abilities of organism. The comparison of the curves fractionation of blood plasma during endotoxemia and in healthy people showed that the patients of the main group there was a significant increase in fractions of A and D, to a lesser extent faction Century There was a tendency to a decrease in blood levels of medium-weight molecules due to their concentration redistribution that may be characteristic only for endotoxicosis

Karimov K.K, Ashurov B.O., Barotov H.N., Sharipov U.L.
In the work of the studied result of the treatment of 73 patients with impairment of long tubular bones of the lower extremities, received at the clinic for emergency and planned manner. All patients were complex clinico-diagnostic approach and appropriate treatment.
The result of the study States that early stable-functional osteosynthesis of a grant minimize disability, early activation of the patients, and also the restoration of the static-dynamic functions and kinematic balance of the musculoskeletal system.

Aim. Evaluation of the effectiveness of existing measures designed at preventing drug use, in particular women.

Sangov M. S., Muradov A. M., Rahmonov E. R.
Results of research of patients are given in work by a typhoid, complicated sharp nephritic insufficiency at which indicators in nephritic haemo dynamics were studied. By researches at different levels of nephritic haemo dynamics it is proved that it directly depends on system or central haemo dynamics, decrease in indicators of UO, UI, SI and in-crease in OPSS, and also pulmonary pressure that leads to authentic decrease in a blood-groove in a nephritic artery which depends on weight of OPN, degree of a gipovolemiya and endogenny intoxication at a typhoid.

A.A. Sharipov, M.F. Narzuloeva, A.H. Tolibov, A.D. Salimov

Nuraliev. Yu. N., Ghaniev. Kh.A., Zubaydova. T.M.,.Samandarov N.Y.
Testing experiments discovered the new unknown phisiological and patogenitical uccuronce connects the breaching of metabolism process on the whole of corbohidrate exchange, prediabetes of patogenes and insulinresistion, mark the beginning metabolitical sindrom with the hard results of illness.
At the state of development the prediabet and insulinresistion the patient must not be use acid food products with cold nature and use products high level alkaline elements.
Only this method of medical prophilaction measures, as recommended and practiced famous Avicena low to stop the developing growth of diabetes and other illness.

Aim. To develop and implement programs for the Epidemiological Monitoring of nosocomial infections in surgical departments, according to the recommendations of the Ministry of Health of the Republic of Tajikistan on the need to create model programs for each department, as well as some projects WHO.

SHARIPOV A.A., NARZULOEVA M.F.
THE DEPARTMENT OF INFECTIOUS DISEASES, EPIDEMIOLOGY, HYGIENE AND ENVIRONMENTAL PROTECTION TIPGPMP
antimalarial drugs. Since the beginning of the 90s in the Republic of Tajikistan epidemiological malaria situation started to deteriorate due to the mass migration of refugees on the territory of Afghan¬istan and their subsequent return to their former place of residence, the sharp weakening of the work of the General and special services, and the conductors real absence of measures to fight against carriers of infection due to economic instability in the Republic of Tajikistan. The article was to study the epidemio¬logical features of the spread of malaria in the Republic of Tajikistan and the factors affecting the malarial situation in preelimination period. The situational analysis is based on data archival materials, annual reports district, regional and Republican centers for combating tropical diseases. Analysis of the archival documents showed that in 1994 and 1995 officially registered 2411 and 6103 cases pathology, respectively, reaching values 29794 patients in 1997. In 2005 as a result of anti-malaria activities registered 2309 malaria cases, in 2008 – 318, in 2010 – 112, in 2011 – 78 and in 2012 – 33 cases. In 2013, however, the incidence of malaria has increased in 1,6 times in comparison with 2012, that is connected with rapid development of road transport infrastructure, construction of new bridges connecting the two States.
The epidemic situation of malaria in the last decade was complicated by the advent of pathogen resis¬tance to

Nurmatov A.A., Nurmatova Z.I., Ibragimova N.I., Rakhimov of M. Н.
Thus, the adiposity, which frequency has an authentic tendency to increase, is a negative background for development of pregnancy and a current of sorts. The complications specified in work authentically are is more often noted at a combination of adiposity to others others disease by diseases. Hence, women with adiposity should be carried to group of risk of development of complications during pregnancy, in sorts and perinatal disease. Frequency of complications of pregnancy and perinatal outcomes are defined by presence and degree of expressiveness НЖО (infringement of a fatty exchange), increase proportionally to increase of degree of adiposity. The further researches will allow to win the answer contract the arisen questions and to optimize tactics of conducting pregnancy and sorts at women with adiposity.

Bustonov M. O., Shamsidinov B. N., Hujamulloev T. Sh., Azizov K. N.
In structure etiological factors neurosensory relative deafness at children mattered: children’s infectious diseases – 67 %; diseases perinatal the period, a Rhesus factor-incompatibility – 18 %; application ototoxicity antibiotics – 8 %; consequences of a craniocereberal trauma – 6 %; genetic rapidly growing the disease form – 1 %.
On severity level sensorineural hearing loss (SHL) the following was marked: heavy degree sensorineural relative deafness (3rd and 4th degree of loss of hearing) – 79 %; 2nd degree of relative deafness – 19 % and accordingly, with 1st degree of relative deafness – 2 %.
Sensorineural relative deafness at children is multifactorial disease, requires early revealing and individual selection of psycho neurological rehabilitation actions.