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    • TRIOIN’S EFFECT ON CARDIOVASCULAR SYSTEM (EXPERIMENTAL WORK)
      06.05.2015

      BAKHROMI M.T.
      THE DEPARTMENT OF CARDIOLOGY WITH THE COURSE OF CLINICAL PHARMACOLOGY TIPGPMP
      The article presents results of studies on the action of a solution trionini on the cardiovas¬cular system. Work is based on the experiment on animals: 20 white rats weighing 200-220 g, cats weight from 3 to 4 kg under uretan anesthesia. Impact trionini on blood pressure were also studied in healthy intact rabbits and rabbits with experimental caused by atherosclerosis. There were 86 series of experiments conducted more than 150 biochemical, 25 haematological analy-ses, prepared 40 drugs from the internal organs of the experimental and control series animals. Heart rate became less 20-22%, the amplitude of the pulse wave increased respiratory activity remained unchanged. There has been little increase of pulse wave and slowing the pace of car¬diac function at 8-10%. In rabbits with atherosclerosis latent phase actions trionini reached 26 seconds, in healthy animals, it was 3-5 sec., that can

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    • DYNAMICS IMMUNOLOGICAL INDICES IN PATIENTS OF CHRONIC GENERALIZED PERIODONTITIS DURING THERAPY WITH MELLINOL
      06.05.2015

      AKHROROVA Z.K., KOMILOV F.M., NOSIROV A.F., FAYZOV K.S.
      THE DEPARTMENT OF ORTHOPEDIC STOMATOLOGY TIPGPMP
      With the purpose of correction of immunological changes in dental patients has been studied the influence of the drug mellinol in the treatment of generalized periodontitis in 32 patients with chronic viral hepatitis b and C. The results obtained show that in the group of patients with chronic viral hepatitis b and C using the drug significantly increased rates of T-lymphocyte subpopula¬tions of T-helpers, a marked increase the number of B-lymphocytes and natural killer cells, and increased the number of cells expressing a chain of the IL-2 receptor and receptor to transferrin that shows a marked improvement periodontal status among the surveyed population. Initially reduced rates of T-lymphocytes and T-helpers, expression markers of activation, as a manifestation of immune dysfunction in patients with chronic viral hepatitis b and C, during the therapy with mellinol significantly

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    • THE DEPENDENCE OF THE INDICES OF CENTRAL HEMODYNAMICS AND SYNDROME OF ENDOGENOUS INTOXICATION FROM ABDOMINAL PRESSURE IN TERMINAL STAGE OF PERITONITIS
      06.05.2015

      MURADOV A.M., AKILOV KH.D., SHUMILINA O.V., KAKHAROV M.A.
      THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY OF TIPGPMP
      THE DEPARTMENT OF ANESTHESIOLOGY AND REANIMATOLOGY TIPGPMP
      THE DEPARTMENT OF SURGERY WITH COURSE OF TOPOGRAPHIC ANATOMY KHD TIPGPMP
      Increasingly important for evaluation of the patient, forecasting the severity of the disease and treatment outcomes acquires indicator of intra-abdominal pressure, which affects all organs and body systems, including the cardiovascular system, manifested by inhibition of the indices of Central hemodynamics. The article presents the results of monitoring of the parameters of Central hemodynamics 24 patients in the terminal stage of peritonitis in the preoperative period and at different times after the surgery. In parallel was monometry intra-abdominal pressure. Clinical observations have shown that an increase intraperitoneal pressure to levels I and II degrees has an identical effect on the indices of Central hemodynamics. Among

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    • ULTRASOUND DIAGNOSTICS THYROID PATHOLOGY IN CHILDREN AND ADOLESCENTS
      06.05.2015

      KASYMOVA S.D., AYUBOVA G.SH., RAHMONOV V.D., BOYMATOVA M.B.
      THE COURSE OF ENDOCRINOLOGY AT DEPARTMENT OF THERAPY TIPGPMP REPUBLICAN CLINICAL CENTRE OF ENDOCRINOLOGY
      In connection with the exceptional importance of the thyroid gland problem of pathology of the organ of children is the focus of endocrinologists. Pathology of the thyroid gland in the regions of iodine deficiency, which includes the Republic of Tajikistan, occupies the leading position in the endocrine pathology in children and adolescents. Diagnostics of thyroid pathology in this category includes a phased investigation with the decision of the question concerning the goitrous increase the authority and assessment of the functional state of the thyroid gland. Many tasks successfully done with the use of ultrasonic technologies. The article suggests the use of ultrasound diagnostics for estimation of structural and functional changes of the thyroid gland, 93 children and adolescents with a duration of pathology from 6 months

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    • COMPARATIVE EVALUATION OF EFFICIENCY APPLICATION OF MODERN METHODS OF DIAGNOSTICS TOXIC BLOOD COMPONENTS DURING ENDOTOXEMIA
      06.05.2015

      TUYCHIBOEVA M.N., MURADOV A.M. SHUKUROV T., SHUMILINA O.V.
      COURSE “LABORATORY WORK” TIPGPMP
      One of the most urgent problems in the structure of modern somatic pathology remains endo¬toxicosis, which is a basic component of the formation of the severity of the General condition. The article presents the results of analysis of toxic blood components 206 patients endotoxemia developed in the result of acute renal failure, peritonitis and septicemia in comparison with the figures of 20 healthy donors. Material for the study served as the blood of patients aged from 17 to 62 years, of which men made up 59,3% of women – 40,3%. The study used biochemical, gel-chromatography and infrared spectroscopic methods of diagnostics indicators token to reflect the level of intoxication. Found that the toxicity index in patients endotoxemia increases by more than 700%, compared with the control. On the basis of carried out research we can conclude that the patients endotoxemia occur intensification of

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    • PERFORMANCE EVALUATION DIAGNOSTIC CENTERS AT THE PRESENT STAGE
      06.05.2015

      SAFAROV Z.SH., AHMEDOV A. A., SAFAROVA T.M.
      NDC MPH RT
      DEPARTMENT OF PUBLIC HEALTH, ECONOMY AND MANAGEMENT BY PUBLIC HEALTH WITH COURSE OF THE MEDICAL STATISTICS TIPGPMP
      At the present stage of development the aim of the health system is the organization of qualita¬tive models of infrastructure and management schemes. In the given aspect the most urgent health problem is to build a high-quality system of medical care. The article summarizes the results of the situational analysis of medical activities and evaluation of diagnostic services at the present stage in the conditions of state financing and transition to full cost accounting in the Republic of Tajikistan. Analysis of normative-legal documents showed that of 2866 institutions of primary health care 3,8% of them are represented by the district and city health centers, 26,5% of rural health centers, 10,8% in the specialized outpatient centers, 58,9 per cent – houses of health. Analysis of the equipment of the medical equipment

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    • STUDY OF THE IMPLEMENTATION OF NATIONAL STANDARDS FOR ANTENATAL CARE FOR PREGNANT WOMEN
      06.05.2015

      SAMADOVA G.A., MULLOEV A.M., DODOBAEVA B.S.
      THE DEPARTMENT OF NURSE WORK IN FAMILY MEDICINE TIPGPMP
      DEPARTMENT OF PUBLIC HEALTH, ECONOMY AND MANAGEMENT BY PUBLIC HEALTH WITH COURSE OF THE MEDICAL STATISTICS TIPGPMP
      Over the past two years the birth rate in the Republic of Tajikistan ranged 29,3-by 28,7 per 1,000 popu¬lation. Along with high fertility, maternal mortality was 45,0 is 37,0 per 100,000 liveborns, the main reasons for which 25% of the cases considered bleeding, 15% and 12% – gynecological infections and eclampsia. The picture presented defined the purpose of the present research is to study the indicators of National standards of antenatal care for pregnant women with an analysis of the correlation between them. Under the supervision were 72 pregnant women aged from 17 to 40 years of age, living in one of the areas with a population of 1722 person. Analysis of work of specialists in antenatal care among women up to 12 weeks of pregnancy showed that only 47,2% of the total

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    • INFLUENCE OF MELDONY ON CARDIOTOXITY OF DOXORUBICINE IN PATIENTS WITH ACUTE LEUKEMIAS
      06.05.2015

      RASULOV U.R., SHARIFOV M.M., SHAMSOV A.T., KHASANOV D.M., RAKHIMOV B.R., SUN’ATULLOEV D.S.
      THE DEPARTMENT OF THE INTERNAL DISEASES №3 TSMU BY NAME ABUALI IBN SINA THE DEPARTMENT OF THERAPY WITH COURSE OF THE ENDOCRINOLOGY TIPGPMP
      Acute leukemia, as a rare disease, is only 3% of human malignancies. The aim of treatment of acute leukemia is eradication of leukemic clone restore normal blood, achieveming long-term disease free survival of patients. This is achieved through the use of myelotoxical anticancer drugs that cause deep aplasia haemopoesis. In the present
      paper summarises the results of the antitumor antibiotic antratcycline stimulants doxorubicin, with a joint appointment cardioprotector meldony. Under the supervision were 147 patients with acute leukemia. Among the observed patients 85 people received chemotherapy initially, 62 people – previously been subjected to chemotherapy effects. For the induction of remission patients of the 1st group was appointed polychemotherapy

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    • THE DEPENDENCE OF THE INDICES OF CENTRAL HEMODYNAMICS AND SYNDROME OF ENDOGENOUS INTOXICATION FROM ABDOMINAL PRESSURE IN TERMINAL STAGE OF PERITONITIS
      06.05.2015

      MURADOV A.M., AKILOV KH.D., SHUMILINA O.V., KAKHAROV M.A.
      THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY OF TIPGPMP
      THE DEPARTMENT OF ANESTHESIOLOGY AND REANIMATOLOGY TIPGPMP
      THE DEPARTMENT OF SURGERY WITH COURSE OF TOPOGRAPHIC ANATOMY KHD TIPGPMP
      Increasingly important for evaluation of the patient, forecasting the severity of the disease and treatment outcomes acquires indicator of intra-abdominal pressure, which affects all organs and body systems, including the cardiovascular system, manifested by inhibition of the indices of Central hemodynamics. The article presents the results of monitoring of the parameters of Central hemodynamics 24 patients in the terminal stage of peritonitis in the preoperative period and at different times after the surgery. In parallel was monometry intra-abdominal pressure. Clinical observations have shown that an increase intraperitoneal pressure to levels I and II degrees has an identical effect on the indices of Central hemodynamics. Among

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    • DEATHS FROM RESPIRATORY DISEASES IN THE REPUBLIC OF TAJIKISTAN
      06.05.2015

      MURADOV A.M., YAKUBOV M.R.
      THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY OF TIPGPMP
      Diseases of respiratory organs are in the lead in the overall morbidity of the population, taking 1st place in the structure of primary morbidity worldwide and deaths from which is on the 4th place in the overall structure of death after circulatory diseases, injuries, poisoning and cancer. In work the analysis of indicators of mortality from respiratory diseases in the Republic of Tajikistan for the period 2000 to 2010. It is revealed, that in structure of total mortality from diseases 2010 diseases occupied the 4-th rank place, after malignant neoplasms. As a result of statistical analysis revealed a trend towards increased mortality among people of working age. This situation is explained by the fact that the majority of persons of working age due to fear of job loss, despite not feeling well, continue to work and this leads to late start of therapy and adherence complications. In 2002,

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    СЛОВО ГЛАВНОГО РЕДАКТОРА

    Наше издание является научно-практическим журналом, в котором публикуются основные научные результаты диссертаций на соискание ученой степени кандидата и/или доктора медицинских наук как нашего института, так и других лечебно-учебных медицинских учреждений, интересные случаи из практики, обзоры литературы, лекции и юбилейные статьи. Журнал выходит 4 раза в год, и каждый номер имеет не менее 80 страниц. Каждая поступающая статья принимается по требованиям, проходит строгий отбор и отдается для выпуска в номер только после рецензирования и обязательного редактирования.

    У нас принято одностороннее слепое рецензирование. Рецензенты уделяют особое внимание содержанию статьи и проверке данных статистической обработки, их соответствие современным требованиям.

      Главный редактор журнала доктор медицинских наук                                                                                                                                                           Мухиддинов Н. Д.

    • The results of analysis of blood characteristics of the patients with sepsis and estimation of markers of its toxic components

      Tuychiboeva M.N., Ahmedova A.A., Mu- hammadnazirzoda N., Muradov A.M.
      Results of analysis of blood characteristics of the patients with sepsis and estimation of its toxic components markers are presented, and revealed that as one of markers adequately reflecting intoxication degree at an early stage of development of pathology levels of molecules of the average weights which research is obviously important and also perspective with the use of gel-chromatographic and Infrared- spectrometer methods can serve.

    • Used folic acid inpregnant women for profiluctic opinc bifide in pructice family doctors

      Mirzoeva Z.A., Okilova M.N., Pulatova S.S.

      The author showed that, in line with current literature, pregnant women should not be advised to keep a diet. All women with a desire to become pregnant should be advised to use folic acid. Women who previously gave birth to a child with a neural tube defect should be offered consultation before pregnancy and should be advised to use 4 mg of folic acid per day.

    • Pregnancy planning in women with the syndrome of pregnancy loss and cytomegalovirus infection

      Rustamova M.S., Radjabova S.A.

      The obtained results of negative cytomegalovirus infection influence on the course of gestation process and the principles of safe motherhood point to carrying of pregnancy planning in women with the syndrome of pregnancy loss. Complex of measures carried out during the predgravidous period was effective in restoring reproductive function in women with pregnancy loss syndrome in cytomegalovirus infection. Prevention and remission of cytomegalovirus infection process, contribute to a favorable outcome of pregnancy, for the majority (71,9%) of women, decrease reproductive fetus loss (3 times) and perinatal mortality (7,4 times) .

    • USING OF PHENOL IN INGROWN NAIL IN PRACTICE OF FAMILY DOCTOR

      MIRZOEVA Z.A., HISOMOVA H.K., KABIROV K.M.
      Using of phenol for treatment in ingrown nail condition decreasing the level of recidivating in¬grown nails that finally brings to traumatism and invalidism of population.

    • ESOPHAGEAL CANCER MORBIDITY IN REPUBLIC OF TAJIKISTAN

      Aim. Performed statistical analysis of the incidence of esophageal cancer in Republic of Tajikistan at 2007-2012.

    • Applying of Clinical experience preparation “Metakrizol” in the treatment of women with cervicitis against the background of benign cervical pathology

      KHAYRIDINOVA J, KHUSEYNOVA M.B, KHABIROVA S.Z.
      The drug of metakrizol has a broad antibacterial l, trihomonotsidnym and antimycotic effect. The use of this drug in the treatment of viral and bacterial cervicitis against dishormonal ectopia of the cervix allows 70% of women to accelerate the elimination of clinical signs of inflammation. However, the therapeutic effect metakrizola significantly reduced in the treatment of inflammation of the cervix against a background of degenerative changes in the cervix caused by scar deformities. It is also effective use of the drug before physical – surgical therapy of cervical cancer, promotes epithelialization of the wound earlier defect (66.7%).

    • CRITERIONS OF CHOICE OF LAPAROSCOPIC CHOLECYSTECTOMY IN PERSONS OF OLDER AGE GROUPS

      Aim. Determine criterions of choose of anesthetic maintenance and laparoscopic cholecystectomy in older age groups.

    • EFFICIENCY OF THE TREATMENT OF CHRONIC PARODONTITIS IN PATIENTS WITH INTERORGAN’S DISORDERS

      Aim. Study of efficiency of the complex treatment of chronic diffuse parodontitis beside patients with disadvantage somatic background in depending of source level unspecific resistance of organism.

    • Standard feature of the individual variety of the functional factor’s organism in patients with periodontal pathology

      Karimov S.M., Makhmudov D.T., Gurezov M.R., Yorakov F.M.
      Pathological changes of the periodontal tissue beside examined patient greatly connection with the general reaction of the organism, which is characterized it is enough high degree and reaction heart and vessels systems. Degree of the defeat periodontal fabric is determined level to accustomed motor activity and each functional type has their own physiological particularities of the factors heart and vessels systems and corresponding to reaction periodontal fabric on damaging factor of the system nature.

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