RASULOV U.R., SHARIFOV M.M., SHAMSOV A.T., KHASANOV D.M., RAKHIMOV B.R., SUN’ATULLOEV D.S.
THE DEPARTMENT OF THE INTERNAL DISEASES №3 TSMU BY NAME ABUALI IBN SINA THE DEPARTMENT OF THERAPY WITH COURSE OF THE ENDOCRINOLOGY TIPGPMP
Acute leukemia, as a rare disease, is only 3% of human malignancies. The aim of treatment of acute leukemia is eradication of leukemic clone restore normal blood, achieveming long-term disease free survival of patients. This is achieved through the use of myelotoxical anticancer drugs that cause deep aplasia haemopoesis. In the present
paper summarises the results of the antitumor antibiotic antratcycline stimulants doxorubicin, with a joint appointment cardioprotector meldony. Under the supervision were 147 patients with acute leukemia. Among the observed patients 85 people received chemotherapy initially, 62 people – previously been subjected to chemotherapy effects. For the induction of remission patients of the 1st group was appointed polychemotherapy by the scheme “7+3”. Patients in group 2 received similar polychemotherapy together with cardioprotector Mildronate. During the treatment of patients of group 1 in 32% of cases were observed sinus tachycardia, atrial and ventricular arrhythmia, changes in segment ST, 7% of cases developed a complete atrioventricular block that shows the development of early cardiac toxicity of doxorubicin. In 19,04% of cases in patients of group 2 were observed ventricular tachycardia, and changes in segment ST.

Tuychiboeva M.N.

Modern methods of laboratory researches of toxic components of blood of endotoxicose patients are analyzed, and are revealed that as one of markers adequately reflecting intoxication degree at an early stage of development of pathology levels of molecules of the average weights which research is obviously important also perspective with the use of gel-chromatographic and Infrared- spectrometer methods can serve.

Nozirov J. Kh., Akhmedov A. A., Rahimov Z. Y.
Detected peculiarities in prevalence IHD Risk Factors in Vanj region population are the key for the development of IHD primary prevention fitting program with allowance for sex and concrete age range.

Khamidov D.B. , Kosimov Z.K. , Khаmidov D.D., Kiyamоv S.E.

In 67 patients with acute peritonitis studied the degree of endogenous intoxication. The efficiency of complex polyfunctional solution reosorbilakt included in the program of infusion therapy for correction of endogenous intoxication in patients with acute peritonitis

AKHMEDOV A., SAMADOVA G.A., MAKSUDOVA Z.YA., ABIDZHANOVA N.N.
DEPARTMENT OF PUBLIC HEALTH, ECONOMICS, MANAGEMENT AND MEDICAL STATISTICS OF TAJIK INSTITUTE OF POST-GRADUATE EDUCATION OF MEDICAL STAFF
DEPARTMENT OF NURSING IN FAMILY MEDICINE OF TAJIK INSTITUTE OF POST-GRADUATE EDUCATION OF MEDICAL STAFF OPEN SOCIETY INSTITUTE “ASSISTANCE FUND” IN TAJIKISTAN
Every year, the incidence of chronic diseases in Tajikistan is growing. By year 2010, the average life expectancy reached 68,3 years, although the figure is not close to pre-war level. There are appeared lonely elderly segment, who suffer under reduced quality of life, and very often death occurs as a result of disease. This picture proves the need to revise the form of medical care of these patients in the final stage of life. Many countries have proved that to meet the needs of these groups of patients, especially when they have decompensation stage and drug treatment is ineffective, palliative care is necessary not only because it is able to improve the quality of life of patient, but also because it is cost efficient. Sociological research of OSI “Assistance Fund” in Tajikistan found out that 76,4% of respondents with various chronic diseases needed palliative care but have not received it.
A group of concerned medical staff started a phase implementation of palliative care in the country’s health system. On the first stage awareness of the health authorities were increased and specialists in palliative care were trained (60 people). Further all education institutions introduced questions on palliative care in the medical educational programs. Parallel undergraduate and postgraduate teachers of nursing education completed coaching courses (185 people). Moreover there were released textbooks for students and teachers guides. In the country graduated new specialists with palliative care knowledge and skills.

MURADOV A.M., AKILOV KH.D., SHUMILINA O.V., KAKHAROV M.A.
THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY OF TIPGPMP
THE DEPARTMENT OF ANESTHESIOLOGY AND REANIMATOLOGY TIPGPMP
THE DEPARTMENT OF SURGERY WITH COURSE OF TOPOGRAPHIC ANATOMY KHD TIPGPMP
Increasingly important for evaluation of the patient, forecasting the severity of the disease and treatment outcomes acquires indicator of intra-abdominal pressure, which affects all organs and body systems, including the cardiovascular system, manifested by inhibition of the indices of Central hemodynamics. The article presents the results of monitoring of the parameters of Central hemodynamics 24 patients in the terminal stage of peritonitis in the preoperative period and at different times after the surgery. In parallel was monometry intra-abdominal pressure. Clinical observations have shown that an increase intraperitoneal pressure to levels I and II degrees has an identical effect on the indices of Central hemodynamics. Among the surveyed, there is reduction of the pay and minute performance of the heart due to the decreasing venous return to the heart. Toxemia accompanied by a decline in heart emission and support perfusion of tissues was provided by a moderate ascending indicators poststrain result of voltage humoral factors. The obtained results showed that patients in the terminal stage of peritonitis observed gypokinetical type of circulation, which is characterized by pronounced hypovolemia and reduced poststrain. Against the background of peripheral vascular insufficiency noted the inconsistency of the Central mechanisms of hemodynamics, due to the depression of the myocardium contractile function. Indicator intraperitoneal pressure is a prognostic criterion of the severity of the syndrome of endogenous intoxication and can be applied at the preoperative stage of examination and treatment of patients in the terminal stage of peritonitis.

Abduloev H.J., Sunatulloev D.S.

Age dimorphism hypertriglyceridemia at the patients with podagra proved to be true also by presence of return correlation relation between a level of whey triglyceridemias and age on the moment of inspection. The frequency of revealing of the increased meaning of AP, on the contrary, has increased with age. It proved to be true also by presence of direct correlation dependence between age and absolute meanings systolic and diastolic of AP. Naturally, that the duration of disease was progressively increased with age of the surveyed patients. Nevertheless, the patients were younger, the in earlier age debuted podagra.

MIRZOEVAZ.A., RAKHIMOVZ.J., NAZIROVAN.K.
Use indicator checking of quality for estimation of efficiency of the treatment patient with arterial hypertension has allowed to compare the existing practical person of the treatment these patient household physician in medical-preventive institutions of Dushanbe, Istaravshan and Konibodom.

MIRZOYEVAZ. A.,ZARIPOVAI.I., DAVLYATOVAD.D.
Plantogrammymethodis simple,affordable,cheap technique.Everyfamily physicianshould possessthispractical skillto detectandprevent the development of flatfootand its complications,whilereferred to a specialistand givecorrect advice.

Kasimova S., Davlatmamadova М.

Problems of IDD spreading in Tajikistan among schoolchildren some regions of the Republic ase still under consideration. Situation with IDD is worsfen by helmint infection among schoolchildren/ these two diseases are worsfen each other and negatively affect physical and mental helth of schoolchildren. Despite the progress the Republic of Tajikistan did not achieve the necessary level of the Program of World Salt iodiration.