DIAGNOSIS AND CORRECTION OF FUNCTIONAL DISORDERS OF LIVER AND LUNG IN PATIENTS WITH SUBDIAPHRAGMATIC LIVER ECHINOCOCCOSIS

DIAGNOSIS AND CORRECTION OF FUNCTIONAL DISORDERS OF LIVER AND LUNG IN PATIENTS WITH SUBDIAPHRAGMATIC LIVER ECHINOCOCCOSIS

Rafikov S.R., *Mahmadov F.I., *Kurbonov K.M., *Rahimov A.R.

DIAGNOSIS AND CORRECTION OF FUNCTIONAL DISORDERS OF LIVER AND LUNG IN PATIENTS WITH SUBDIAPHRAGMATIC LIVER ECHINOCOCCOSIS

Department of Surgical Diseases of the State Education Establishment “Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan”

*Department of Surgical Diseases №1 of the Tajik Medical State University named after Abua- li-ibn-Sino

Aim.Improvement of results of treatment of subdiaphragmaticechinococcosis of liver and its complications.

Materials and methods. The present research is based on the analysis and treatment of 76 patients with hepatic echinococcosis of subdiaphragmatic location. The vast majority were persons older than 40 years. There were 33 males (43,4%) and 43 women (56,6%). Complicated forms of echinococcosis was observed in 63,1% (n=48) patients (abscess-27, a breakthrough in the bile way — 21).

Results.Echinococcosis of the liver accompanied by significant destruction of hepatocytes, a violation of indicators of the level of proinflammatory cytokines and nitric oxide, especially in the complicated course and subdi-aphragmatic location, indicating that altered functions of liver and lungs. With the growth of volume of hydatid cysts in the subdiaphragmatic space and in long-term course of the disease violated ventilation and gas exchange function of the lungs.

Conclusion. To patients with hepatic echinococcosissubdiaphragmatic localization advisable to conduct in the preoperative period antihypoxic therapy to significantly improve functional state of the liver and lungs.

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