• ANTIDESTRUCTIVE ACTION OF GLUCOCORTICOIDS AT EARLY REUMATOID ARTHRITIS

    Ahunova N.T., Holova Z.U., *Niyazov F.I.

    ANTIDESTRUCTIVE ACTION OF GLUCOCORTICOIDS AT EARLY REUMATOID ARTHRITIS

    Department of Therapy of the State Education Establishment “Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan”

    *Department of Internal Disease № 3 of the Tajik Medical State University named after Abuali-ibn-Sino

    Aim. Study of antidestructiveactionsofglucocorticosteroids on the background of the basic treatment of early rheumatoid arthritis by methotrexate.

    Materials and methods. Present results of treatment of 42 patients (all women) in the age of 32 to 58 years (mean 45 years). Duration of disease from 0,5 to 2 years with a valid RA (ARA criteria, 1987), observed during the year. Exclusion criteria were the presence of stomach ulcer or 12-duodenal ulcer. Patients with IV stage of radiographic disease. All patients were divided into two groups: 1 – 22 persons receiving methotrexate 10 mg per week and glucocorticosteroids7.5mg

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  • OPTIMIZED APPROACH TO THE TREATMENT OF LIMB FRACTURES IN PATIENTS WITH ORTHOPEDIC TRAUMA

    Ahmedov Sh.M., Sirodzhov K.H., Muradov A.M., Holov D.I., Rahimov A.T.

    OPTIMIZED APPROACH TO THE TREATMENT OF LIMB FRACTURES IN PATIENTS WITH ORTHOPEDIC TRAUMA

    Department of Traumatology and Orthopedics of the State Education Establishment “Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan”

    Aim.Optimization of diagnostics and surgical treatment of fractures in patients with multiple injuries.

    Materials and methods. The work is based on analyzing results of diagnosis and treatment of 183 patients in the period 2001-2013, which were divided into 2 groups. In the main group osteosynthesis of fractures optimized with the lipid spectrum of blood plasma, in the control group treatment of fractures is traditionally held. The examination program of patients included: clinical examination, beam diagnostics, clinical laboratory tests, the study of the concentration of total lipids, catalase, atherogenic index calculation, the concentration of cholesterol,

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  • TWO CASES OF LATE DIAGNOSIS OF ACROMEGALIA

    Rahmonov V.D., Kasymova S.D.

    TWO CASES OF LATE DIAGNOSIS OF ACROMEGALIA

    Course of Endocrinology of the State Education Establishment “Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan”

    This article describes 2 cases of late diagnosis of acromegaly caused by pituitary adenomas. Showing difficulties primary diagnosis of the disease. Demonstrated experience in application of modern methods of drug therapy Sando- statin LAR in adequate doses to the achievement of the inactive phase of the disease

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  • PRIMARY CEREBRAL STROKE PREVENTION

    Abdurahmanova R.F., Izzatov K.N., Hadibaeva G.R., Sharifova B.A., Rashidova O.A.

    PRIMARY CEREBRAL STROKE PREVENTION

    Department of Neurology and Medical Genetics of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

    The article describes main directions of primary prevention of cerebral stroke. It is shown that the system of primary prevention of stroke is divided on population strategy and high-risk strategy. Population strategy is aimed at informing the public about modifiable risk factors associated with lifestyle, and possibility of their correction. A population strategy is aimed at informing the public about modifiable risk factors associated with lifestyle, and possibility of their correction. Strategy of a high risk means early identification of patients in high risk groups followed by preventive medicamental and (if necessary) of vascular surgery treatment. Thus, changes in lifestyle, adequate antihypertensive,

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  • SOME FEATURES OF CROSS BORDER TRANSMISSION OF MALARIA TO THE REPUBLIC OF TAJIKISTAN IN PREDELIMINATION PERIODS

    *Sharipov A.A., *Narzuloeva M.F., **Saiburkhonov D.S.

    SOME FEATURES OF CROSS BORDER TRANSMISSION OF MALARIA TO THE REPUBLIC OF TAJIKISTAN IN PREDELIMINATION PERIODS

    *Department of Infectious Diseases of the State Educational Establishment “Institute of Postgraduate Education in Health Sphere of the Republic of Tajikistan”

    **State Establishment “Republican Center for control of Tropical Diseases”

    Aim. To explore some features of cross-border malaria transmission in the territory of the Republic of Tajikistan in predelimination periods.

    Materials and methods. Are used reporting documentation of the National Centre for Combating Tropical Diseases (Malaria), medical history of patients with malaria hospitalized in Clinical Infectious Diseases Hospital and Medical Center of Dushanbe. In the subsequent were calculated the arithmetic mean value of all the obtained results, and also evaluation given to them.

    Results. During the analyzed period in the country there is a decrease

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  • VALUE OF THE WEBER TEST IN DIAGNOSIS OF DIFFERENT FORMS OF OTOSCLEROSIS

    Shamsidinov B.N., *Azizov K.N., Muhtorova P.R., Shaydoev S.S.

    VALUE OF THE WEBER TEST IN DIAGNOSIS OF DIFFERENT FORMS OF OTOSCLEROSIS

    Department of Otorhinolaryngology of the State Educational Establishment «Institute of Postgraduate Education in Sphere of Republic of Tajikistan»

    *National Medical Center of Republic of Tajikistan

    Aim. To evaluate the impact of sound perception and sound conduction disorders in otosclerosis on the lateralization of sound, to determine the forms of disease, in which the experience of Weber is most effective, set the value of the experiment at two intensities for detecting of lesions of cochlea in otosclerosis.

    Materials and methods. We analyzed audiograms of 100 patients with otosclerosis. Information of threshold tonal audiometry, binaural balance of loudness and also difference in the threshold of differentiation on 500 and 2,000 Hz were compared with experimental results of Weber.

    Results.Revealed that dependence of lateralization

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  • AZIKAV IN COMPLEX TREATMENT OF HERPES ZOSTER

    Salimov B.M, Kasymov O.I, Munieva S.H.

    AZIKAV IN COMPLEX TREATMENT OF HERPES ZOSTER

    Department of Dermatology and STIs of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

    Aim.A study of the effectiveness of atsikav (acyclovir) in the complex treatment of patients with herpes zoster.

    Materials and methods. Under observation were 48 patients with herpes zoster. Among the patients with herpes zoster were 32 (66,2%) men and 16 (33,3%) women aged between 18 and 84 years. Methods: clinical, statistical.

    Results. Treatment of patients has gone well. Side effects and complications of the drugs were not at any patient. The results showed the effectiveness of the treatment by complex therapy. So excellent results (clinical recovery) with typical form of herpes zoster in the end of the 1st week of observation in the complex therapy was achieved in 83.3% of patients and after 12-14 days in 100%. Among patients with

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  • EXPERIENCE IN DEVELOPMENT AND INTRODUCTION OF CLINICAL PROTOCOLS ON CHILDHOOD DISEASES IN MEDICAL PRACTICE OF REPUBLIC OF TAJIKISTAN

    *RahmatulloevSh.R., **SaidmuradovaG.M., *RahmatulloevaS.I., TolibovA.H.

    EXPERIENCE IN DEVELOPMENT AND INTRODUCTION OF CLINICAL PROTOCOLS ON CHILDHOOD DISEASES IN MEDICAL PRACTICE OF REPUBLIC OF TAJIKISTAN

    *The Ministry of Health and Social Protection of Population of Republic of Tajikistan

    **Department of Pediatric Infection Diseases of the Tajik State Medical University

    Aim.Studying experience of development of clinical protocols in other countries to improve national clinical protocols for childhood diseases.

    Materials and methods. During the period from 2002 to present time, total were developed 4 clinical guidelines and protocols (CP) on the main diseases of childhood. Main purpose of creating of CP is to ensure the target groups with an exhaustive instructions for making decisions on their use in clinical practice. Rational use of clinical protocols depends of complying of all design rules with the search and evaluation of the best available evidence. Basic requirements

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  • ANALYSIS OF MORBIDITY OF COLORECTAL CANCER IN REPUBLIC OF TAJIKISTAN

    *Rasulov S.R., **Karimov A.M.

    ANALYSIS OF MORBIDITY OF COLORECTAL CANCER IN REPUBLIC OF TAJIKISTAN

    *Department of Oncology of the State Educational Establishment «Institute of Postgraduate Education in Health Sphere of Republic of Tajikistan»

    **State Establishment “Republican Oncological Scientific Center” of the Ministry of Health and Social Protection of population of Republic of Tajikistan

    Aim. To perform statistical analysis and identify the most characteristic features of colorectal cancer in the population of Republic of Tajikistan.

    Materials and methods. Clinical data of 115 patients with colorectal cancer in the age of 18 to 92 years, who were treated in department of oncoproctourology of State Establishment “Republican Oncological Scientific Center” of Ministry of Health of Republic of Tajikistan in 2012 was studied. Tumor morphologically verified in all patients. In a planned regularity were hospitalized 89 patients, by emergency indications – 26 patients. To

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  • EFFECTIVENESS OF REHABILITATION OF SURDUSPEDAGOGICAL SCHOOL-AGE CHILDREN WITH SENSORINEURAL HEARING LOSS COMBINED WITH CEREBRAL PALSY

    *OchilzodaA.A., **SolievaM.S.

    EFFECTIVENESS OF REHABILITATION OF SURDUSPEDAGOGICAL SCHOOL-AGE CHILDREN WITH SENSORINEURAL HEARING LOSS COMBINED WITH CEREBRAL PALSY

    *Khujand City Health Center number 2

    **Sughd Regional Hospital, Tajikistan

    Aim.Evaluating the effectiveness of surduspedagogical rehabilitation of sick children with sensorineural hearing loss in combination with cerebral palsy by modern methods of medical treatment, physical therapy action and serdusped- agogical rehabilitation methods, using stationary sound-amplifying device “Audio filter MT”.

    Materials and methods. Were examined 75 children aged from 7 to 14 years for the period of 2009-2013 in the conditions of the Regional SurduslogicalCenter.In medical, psychological and pedagogical department of the City Health Center №2 of Khujand. Were studied 41 boys (54.6%) and 34 girls (45.3%). All the patients underwent complete otorhinolaryngological examination, hearing test using tone threshold and speech audiometry,

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