* RAKHIMOV Z.YA., **KUDRATBEKOVA., * NARZULLAYEVA A.R.
**CARDIOLOGISTS ASSOCIATION OF THE REPUBLIC OF TAJIKISTAN
*DEPARTMENT OF CARDIOLOGY WITH THE COURSE OF CLINICAL PHARMACOLOGY TIPGPMP
The article is devoted to the study of the use of Meldrony in 30 patients with chronic coronary heart disease, stable angina of II-III class combined with arterial hypertension of II degree with high and very high risk of cardiovascular complications in conditions, Midlands Gorno-Badakhshan Autonomous region of Tajikistan. Among the examined patients on the background of the drug Meldrony in a daily dose of 1000 mg, showed a significant improvement cardiohaemodynamic indicators. Simultaneously, a decrease of the average frequency of angina attacks a day with 2,77±0,26 to 1,52±0,17. Also noted a decrease of the daily quantity of consumed nitroglycerin from 2,4 to±0,23 to 1,4±0,16 and significant increase of tolerance to physical activity detected test 6-minute walk from 388±33 m up to 512±39 m

SHUMILINA O. V., DOSTIEVA Z.A., MURADOV A.M., KHAMIDOV J.B.
At patients with the peritonitis, caused pancreatonecrosis, decrease in common concentration of an albumin since its centers of binding are blocked by the toxic – ligands is noted. Respectively we receive low indexes of efficiency concentration of an albumin. It testifies to decrease in transport function of an albumin, depressing of detoxicating function of a liver where the albumin on P-450 cytochrome is released from toxiferous ligand. Inherently, this test reflects a hydrophobic component of intoxication at peritonitis.

RASULOV S.R.
КАФЕДРА ОНКОЛОГИИ ТИППМК
The work presents the results of scientific and statistical analysis of materials of primary breast cancer patients registered at the polyclinic of the Republican oncological scientific center of the Republic of Tajikistan in 2012. Analysis of data of out-patient cards of 215 patients ages 25 to 97 years, with the presence of a tumor in the breast. Study of age-related data breast cancer patients showed that up to 24 years of age are not encountered a single case of the disease. In the 25-29 age noted only 3,3% of women with this pathology. The peak incidence of pathology occurs at the age 45-49 years, accounting for 16,7% of the total number of women. Analysis of statistical material has shown that starting from the age of 60, breast cancer risk is gradually fading. Of the total number of patients for 64,7% of the нозологией were residents of rural areas, 35,3% is urban. On топическому location of the cancer

Mukhamadieva S.M., Hayriddinova D., Sultanova M.

Thus, conducted research has let to provide medical and social characteristics of women of reproductive age with pathological processes of the cervix, which is represented by housewives (68.8%), repeated (37.3%) – and multiparous (39.6%), with low health index, frequent to abortion (48.8%), those who do not use barrier methods of contraception (83.1%) and those with Cancer history (10.1%). Particular at risk group for the development of pathological processes of the cervix, are sexually active adolescents, which typically have dishormonal disorders and early occurrence of inflammatory processes of the lower part of the genitals. The high frequency of hyperplastic processes in women of late reproductive age is a risk factor for precancerous cervical disease. The main factors determining the development of pathological processes in the cervical region of high fertility are: early sexual activity (22.9%), change of sexual partners (11.4%),

DOSTIEVA Z.A., SHUMILINA O.V., MURADOV A.M., HAMROKULOV A.A.
THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY TIPGPMP
In 15 patients with pancreonecrosis complicated by the terminal phase of peritonitis, we estimated the effect of indirect electrochemical blood oxidation on the state of the detoxification function of the lungs by intravenous 0,06% solution of sodium hypochlorite. To study the detoxification function of the lungs compared the blood of the right ventricle of the heart and arterial blood from radiotherapy or femoral artery, taken simultaneously. Study was carried out after 1 and 4-6 h after infusions of the mentioned solution. If, prior to the infusion of sodium hypochlorite concentration of urea and creatinine in the blood drains were reliably higher than in streams to the light respectively by 20,9% and 12,9%, for 1 hour, these figures are reduced to the respective indicators of 18,2% and 7,6%, and after 6 hours of light to see themselves their detoxifying that

MURADOV A.M., AKILOV KH.D., SHUMILINA O.V., KAKHAROV M.A.
THE DEPARTMENT OF EFFERENT MEDICINE AND INTENSIVE THERAPY OF TIPGPMP
THE DEPARTMENT OF ANESTHESIOLOGY AND REANIMATOLOGY TIPGPMP
THE DEPARTMENT OF SURGERY WITH COURSE OF TOPOGRAPHIC ANATOMY KHD TIPGPMP
Increasingly important for evaluation of the patient, forecasting the severity of the disease and treatment outcomes acquires indicator of intra-abdominal pressure, which affects all organs and body systems, including the cardiovascular system, manifested by inhibition of the indices of Central hemodynamics. The article presents the results of monitoring of the parameters of Central hemodynamics 24 patients in the terminal stage of peritonitis in the preoperative period and at different times after the surgery. In parallel was monometry intra-abdominal pressure. Clinical observations have shown that an increase intraperitoneal pressure to levels I and II degrees has an identical effect on the indices of Central hemodynamics. Among

Aim. Surgical results improvement of musculo-skeletal system fractures in polytrauma acuity.

Sodiqov A. M., Murodov A. M., Hamroqulov A. A., Shumilova O. V.
The data obtained indicate excessively slow recovery of lost functions, which is most intense during the first 2 – 3 years and indicate the need for prolonged recovery of renal function for more than 6-7 years, deterioration of renal function contributed to: a chronic underlying disease (chronic glomerular – pyelonephritis, anemia, and subsequent pregnancy and childbirth in the background is not completely recovered renal function). Therefore, this group of patients should be on the dispensary to the full restoration of the functional usefulness of the kidneys, at least 2-3 years, and patients with chronic renal failure observed in different stages – for life

Nazirova M.A, Ahmedov А.A, Kasymova M. K.
On the basis of the analysis of statistical materials of the State agency at the Government of Republic Tajikistan, the Republican Center of medical statistics and the information of Ministry of Health of the Republic Tajikistan, given annual reports Hudzhand regional Centers of Reproductive health, and also data of annual reports of obstetrical establishments of Sogd area for 2001-2010 it is established, that among women of reproductive age widespread abortion practice that testify to unsatisfied requirement of women of active reproductive age for contraception and about necessity of carrying out of actions for expansion of access of target groups to services in the field of reproductive health and family planning.

Abdufatаev T.A., Ikromov T.Sh., Rofiev R.R., Ibodulloev H.U.

Activities of kidney diseses, is a nefrolitiasis Reguied of best estimate. First of all the principle of determine of spoiling aetivities kidney in time, the step of infection of them, stepts of different is petomorfology, the right of diagnosis is dependence of treatment.