• TRIOIN’S EFFECT ON CARDIOVASCULAR SYSTEM (EXPERIMENTAL WORK)

    BAKHROMI M.T.
    THE DEPARTMENT OF CARDIOLOGY WITH THE COURSE OF CLINICAL PHARMACOLOGY TIPGPMP
    The article presents results of studies on the action of a solution trionini on the cardiovas¬cular system. Work is based on the experiment on animals: 20 white rats weighing 200-220 g, cats weight from 3 to 4 kg under uretan anesthesia. Impact trionini on blood pressure were also studied in healthy intact rabbits and rabbits with experimental caused by atherosclerosis. There were 86 series of experiments conducted more than 150 biochemical, 25 haematological analy-ses, prepared 40 drugs from the internal organs of the experimental and control series animals. Heart rate became less 20-22%, the amplitude of the pulse wave increased respiratory activity remained unchanged. There has been little increase of pulse wave and slowing the pace of car¬diac function at 8-10%. In rabbits with atherosclerosis latent phase actions trionini reached 26 seconds, in healthy animals, it was 3-5 sec., that can

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  • DYNAMICS IMMUNOLOGICAL INDICES IN PATIENTS OF CHRONIC GENERALIZED PERIODONTITIS DURING THERAPY WITH MELLINOL

    AKHROROVA Z.K., KOMILOV F.M., NOSIROV A.F., FAYZOV K.S.
    THE DEPARTMENT OF ORTHOPEDIC STOMATOLOGY TIPGPMP
    With the purpose of correction of immunological changes in dental patients has been studied the influence of the drug mellinol in the treatment of generalized periodontitis in 32 patients with chronic viral hepatitis b and C. The results obtained show that in the group of patients with chronic viral hepatitis b and C using the drug significantly increased rates of T-lymphocyte subpopula¬tions of T-helpers, a marked increase the number of B-lymphocytes and natural killer cells, and increased the number of cells expressing a chain of the IL-2 receptor and receptor to transferrin that shows a marked improvement periodontal status among the surveyed population. Initially reduced rates of T-lymphocytes and T-helpers, expression markers of activation, as a manifestation of immune dysfunction in patients with chronic viral hepatitis b and C, during the therapy with mellinol significantly

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