The manuscript must be submitted in Russian and/or English and prepared in MS Word:

• Font: Times New Roman, size 14 for the main text; size 12 for abstracts;
• Line spacing: 1.5;
• Margins: top – 2.0 cm; bottom – 2.0 cm; left – 2.0 cm; right – 2.0 cm;
• Page numbering: All pages, starting from the title page, must be numbered consecutively.

• Full-length original articles and literature reviews: no more than 18 pages (including all sections).
• Case reports: no more than 10 pages.

• Title page (separate).
• Abstract and keywords in Russian, English, and Tajik.
• Main text: Introduction/Background, Study Objective, Materials and Methods, Results, Discussion, Conclusion.
• References (Vancouver style).
• Tables and figures (if necessary).

• Length: 250–300 words in each language (Russian, English, Tajik).
• Sections: Objective, Materials and Methods, Results (with specific data), Conclusions.

• Length: at least 150 words.
• A brief summary of the content without division into sections.

• Number: 5–7 words.
• Selected according to MeSH (https://www.nlm.nih.gov/mesh/meshhome.html).
• Provided in all languages of publication.

• Brief literature review (publications from the last 5–7 years, with rare exceptions of 1–2 sources from earlier years).
• Relevance, scientific novelty, practical significance, controversial and unresolved issues.
• Do not present results or conclusions of the authors' own study.

The objective must be clear, specific, and derived from the background.

• Study design: type (prospective, retrospective, randomized, cohort, cross-sectional, etc.), location and period.
• Participants: inclusion/exclusion criteria, sample characteristics, randomization, representativeness.
• Methods: detailed description for reproducibility, equipment with manufacturer, drugs (INN), use of AI (detailed description, human verification of accuracy).
• Ethics: ethics committee approval number, adherence to the Declaration of Helsinki, informed consent, data confidentiality.
• Statistics: software with version, statistical methods, significance level (p<0.05), confidence intervals.

• Logical sequence, main results first.
• Absolute numbers and percentages.
• Do not duplicate data from tables in the text.

• Summary of key findings, comparison with literature, statistical and clinical significance, study limitations.
• Avoid repeating data from "Introduction/Background" and "Results".

• Answers to the research questions, concise and clear recommendations for improvement.
• Avoid unsubstantiated statements.

• Reports on incomplete or planned studies will not be accepted.
• In one issue: no more than 2 works by the same author.
• Students may be authors if they meet the authorship criteria.

• Bears primary responsibility for communication with the journal, ensures compliance with requirements, must be available throughout the publication process.

• Mandatory registration before enrollment of the first participant (registries: ClinicalTrials.gov, WHO ICTRP, national registries). The study protocol must be available.

• Any identifying information must be excluded. Patient photographs must be provided in a form that precludes identification. Written consent is required if complete anonymization is impossible. Blurring of personal data on radiographs and other images.

• Compliance with international standards for animal care and use, approval from relevant committees, minimization of animal suffering.

• Mandatory declaration of all cases of AI use, detailed description in the relevant section. AI cannot be an author or co-author. Verification of the accuracy of all results obtained with AI.

• Vancouver style according to ICMJE (link).
• Numbering in order of citation, references in square brackets: [1, 2], [1–4], [3, 5–8].
• Font size 12, line spacing 1.5.

• Original articles: up to 15 sources from the last 5-7 years (rare exceptions 1-2 older sources).
• Literature reviews: no more than 30 sources.
• Case reports: no more than 10 sources.

• Surnames and initials of all authors; if >6 authors, list first 6 followed by "et al."
• Mandatory transliteration (BGN or BSI style).
• Check for retracted articles.

• Place after first mention. Provide both in the text and as a separate MS Word file.
• Numbering in Arabic numerals, self-explanatory titles, columns/rows named according to data.
• Statistical data with indication of methods.

• Quality: at least 300 dpi. Size: at least 80×80 mm (approx. 1000×1000 pixels). Format: TIFF or JPEG (separate files).
• Captions informative and self-explanatory.

• Provide both as a figure in the text and as an MS Excel file. Clarity, contrast, correspondence to text.

• Indicate staining method and magnification, include scale bars if necessary.

• Transparent peer review process.
• Single-blind peer review (authors do not know reviewers).
• At least 2 independent expert reviewers per article. Reviewers maintain confidentiality.
• International experts when necessary.

• Scientific novelty and relevance, methodological quality, ethical compliance, quality of presentation, relevance to journal scope.
• Reviewers must ensure objectivity and confidentiality, not post materials in AI. If conflict of interest, decline to review.

• Accept without changes; accept after revision; reject with possibility of resubmission; reject.
• After receiving recommendations, author must revise. If revision refused, written withdrawal required. If revised version not received within three months, editorial board removes the article.
• Negatively evaluated manuscripts are not published or returned. Evaluations are kept for five years.