The manuscript should be submitted in Russian or English and typed in MS Word:

• Font: Times New Roman, size 14
• Line spacing: 1.5
• Margins: top – 2.0 cm; bottom – 2.0 cm; left – 2.0 cm; right – 2.0 cm
• Numbering: All pages, starting from the title page, must be numbered consecutively

• Full-length original article: 8–12 pages, including all sections except references
• Review article: 12–15 pages
• Case reports: no more than 8 pages

The manuscript must consist of the following elements:

1. Title page with complete author and article information
2. Abstract in Russian, English, and Tajik with keywords
3. Main body must contain the following sections:
   • Introduction (relevance)
   • Aim of the study
   • Materials and Methods
   • Results
   • Discussion
   • Conclusion
4. References, formatted in Vancouver style
5. Tables and figures (if necessary)

For each author, provide:

• Full last name, first name, and patronymic
• Academic degrees and titles
• Position and affiliation (institution name and department)
• Postal code and full address
• Contact phone numbers
• Email address

• Funding sources: grants, equipment, medications
• Conflict of interest declaration (financial and non-financial)
• Use of AI technologies (if applicable)

• Length: 250-300 words in each language
• Required sections:
  1. Relevance/Aim
  2. Materials and Methods
  3. Results (with specific data)
  4. Conclusion

• Length: at least 150 words
• Content: Brief summary without section division

• Number: 5-7 words
• Selection: According to Medical Subject Headings (MeSH)
• Indication: In all publication languages

• Brief literature review (publications from the last 5-10 years)
• Relevance of the problem
• Scientific novelty and practical significance
• Controversial and unresolved issues
• Clear statement of the study aim
• Avoid: data and conclusions from your own study

Study Design:

• Type of study (prospective, retrospective, randomized, etc.)
• Location and time of conduct

Study Participants:

• Inclusion and exclusion criteria
• Sample characteristics (age, sex, ethnicity)
• Randomization (if applicable)
• Sample representativeness

Research Methods:

• Detailed description of methods for reproducibility
• Equipment with manufacturer indication
• Medications (international nonproprietary names)
• Use of AI technologies (detailed description if applicable)

Ethical Aspects:

• Ethics committee approval number
• Compliance with the 2024 Declaration of Helsinki
• Informed consent of participants
• Data confidentiality

Statistical Analysis:

• Software with version indication
• Statistical methods
• Significance level (usually p<0.05)
• Confidence intervals

Results:

• Logical sequence of presentation
• Primary results first
• Absolute numbers and percentages
• Do not duplicate data from tables in the text

Discussion:

• Brief summary of main findings
• Comparison with literature data
• Statistical and clinical significance
• Study limitations
• Avoid repeating data from the Introduction and Results sections

Conclusion:

• Answers to the stated objectives
• Concise and clear recommendations for improvement
• Avoid unsubstantiated statements

• Maximum number of authors: 8 for original articles, 6 for other types
• In one issue: no more than 2 works by the same author
• Students can be authors if they meet the criteria

• Primary responsibility for communication with the journal
• Ensures compliance with all requirements
• Must be available throughout the publication process

• Mandatory registration before the first participant is enrolled
• Permissible registries: ClinicalTrials.gov, WHO ICTRP, national registries
• Study protocol must be available

• Any identifying information is excluded
• Masking faces in photographs is insufficient
• Written consent if complete anonymization is impossible
• Obscuring data on radiographs and other images

• Compliance with international standards for care and use
• Approval by relevant committees
• Minimization of animal suffering

• Mandatory declaration of all cases of use
• Detailed description in the appropriate section
• AI cannot be an author or co-author
• Verification of accuracy of all results obtained with AI

• Vancouver style according to ICMJE
• Numbering in order of citation in the text
• References in square brackets [1, 2] or [1–4] or [3, 5–8]

• Original articles: 10-20 sources
• Literature reviews: no more than 30 sources
• Case reports: no more than 15 sources

• Placement in the text after first mention
• Numbering in Arabic numerals
• Headings must be self-explanatory
• Format: Microsoft Office Word
• Statistical data with indication of methods

• Quality: at least 300 dpi
• Size: at least 80×80 mm (approximately 1000×1000 pixels)
• Format: TIFF or JPEG (separate files)
• Captions must be informative and self-explanatory

• Double-blind peer review
• Minimum of 2 reviewers for each manuscript
• International experts if necessary

• Scientific novelty and relevance
• Methodological quality
• Compliance with ethical standards
• Quality of presentation
• Relevance to the journal's scope

• Accept without changes
• Accept after revision
• Reject with possibility of resubmission
• Reject