Abstract

Summary

To evaluate the clinical effectiveness of комплекс treatment of infected burn wounds of the lower extremities in patients with type 2 diabetes mellitus compared to conventional therapy.
 

Materials and Methods

A prospective controlled study included 48 patients with infected burn wounds (grade II–III B) and type 2 diabetes mellitus. Patients were randomized into two groups: the main group (comprehensive treatment including surgical debridement, modern wound dressings, negative pressure wound therapy (NPWT), low-level laser therapy (LLLT), and metabolic correction) and the control group (conventional therapy).The outcomes included wound cleansing time, bacterial contamination, granulation and epithelialization rates, glycemic control, and complication frequency.
 

Results

Wound cleansing was significantly faster in the main group (5.6±1.4 vs 10.3±2.1 days, p<0.01). Bacterial load decreased to ≤10² CFU/g by day 14. Granulation occurred earlier (day 6-7 vs 11-13), and epithelialization was completed faster (22±4 vs 36±6 days). Blood glucose decreased to 7.9±1.6 mmol/L. Amputations were observed only in the control group (12.5%).
 

Conclusion

Комплекс therapy significantly improves healing outcomes and reduces complications in diabetic patients with infected burn wounds.
 

Keywords

diabetes mellitus burn wounds infected wounds negative pressure wound therapy laser therapy granulation amputations

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References

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