Аннотация

Цель
Construction and evaluation of the effectiveness of a therapeutic model using carbon dioxide in periodontal diseases.
Материал и методы
60 laboratory rats of the Wistar line served as biological material for the study. The experimental animals were surgically modeled into a periodontitis clinic, after which some of the animals underwent carboxytherapy, leaving the other part of the animals without specif-ic treatment. Carboxytherapy was performed in two modes. After removing the animals from the experiment, micro-preparations of the damaged jaw were made and the histological picture was compared.
Результаты
The use of injectable carboxytherapy, accompanied by an increase in carbon dioxide levels, contributed to the regeneration of damaged periodontal tissues and the elimination of the ac-idotic state. At the end of the study, bone destruction with a tendency to sponging was detected in the animals of the control group. fibroblast-like cells were found in the interosseous spaces. We con-sidered, among other things, the approximation of its structure to a spongy substance as evidence of the destruction of the alveolar bone. In contrast to the picture in the control group, the histological parameters of animals exposed to CO2 did not differ from the norm
Заключение
An experimental study has shown that carbon dioxide injections can be used to improve tissue trophism and stimulate compensatory processes in the treatment of inflammatory per-iodontal diseases

Ключевые слова

periodontitis carboxytherapy carbon dioxide experiment modeling therapy.

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Список литературы

  1. Kolsanov A.V., Trunin D.A., Khaikin M.B [et al.] Vozmozhnosti ispolzovaniya karbokciterapii pri zabolevaniyakh parodonta: dokklinicheskoe eksperimentalnoe issledovanie [Use of carboxy-therapy in the treatment of periodontal diseases: a preclinical experimental study]. Kybanskiy nauchniy meditsinskiy vestnik – Kubani scientific medical herald, 2024, N 31(1), pp. 27-38.
  2. Svizhevskaya Ju.A. Karbokciterapiya [Carboxytherapy]. Flagman nauki - Flag officer of the science, 2024, N 5(16), pp. 226-230.
  3. Serikova A.A., Iordanishvili A.K., Sjldatova L.N. Effektivnost metoda invazivnoy karbokciterapii pri lechenii bolevoy disfunkcii bisochno-nizhnechelyustnogo sustava [Invasive carboxytherapy effecctiveness in the treatment of painful temporomandibular joint dysfunction]. Parodontologija- Parodontology, 2022, N 27(4), pp. 52-357.
  4. Ahramiyanpour N, Shafie’ei M, Sarvipour N. [et al.] Carboxytherapy in dermatology: A systematic review. J Cosmet Dermatol., 2022, Vol. 21, N 5, pp. 1874-1894. [https://doi.org/10.1111/jocd.14834](https://doi.org/10.1111/jocd.14834)
  5. Bagherani N., Smoller B.R., Tavoosidana G. [et al.]. An overview of the role of carboxytherapy in dermatology. J Cosmet Dermatol., 2023, Vol. 22, N 9, pp. 2399-2407. [https://doi.org/10.1111/jocd.15741](https://doi.org/10.1111/jocd.15741)
  6. Brochado T.M., de Carvalho Schweich L., Di Pietro Simões N. [et al.]. Carboxytherapy: Controls the inflammation and enhances the production of fibronectin on wound healing under venous insufficiency. Int. Wound J., 2019, Vol. 16, N 2, pp. 316-324. [https://doi.org/10.1111/iwj.13031](https://doi.org/10.1111/iwj.13031)
  7. Prazeres J., Lima A., Ribeiro G. The effect of carbon dioxide therapy on skin wound healing. Biomedicine, 2025, Vol. 18, N 13(1), pp. 228. [https://doi.org/10.3390/biomedicines13010228](https://doi.org/10.3390/biomedicines13010228)
  8. Krumpuzos G., Aurora G., Kassir M. [et al.]. Carboxytherapy in dermatology. Clinical dermatology, 2022, Vol. 40, N 3, pp. 305-309. [https://doi.org/10.1016/j.clindermatol.2021.08.020](https://doi.org/10.1016/j.clindermatol.2021.08.020)
  9. Sakai Yu., Miwa M., Oe K. [et al.]. A new system for percutaneous administration of carbon dioxide, causing an «artificial Bohr effect» in the human body. PLoS One, 2011, N 6(9), pp. 24-37. [https://doi.org/10.1371/journal.pone.0024137](https://doi.org/10.1371/journal.pone.0024137)