Аннотация

Резюме

.

Цель

To study the epidemiological features of leukemia in children under 14 years in the Republic of Tajikistan during the period 2018–2024, including incidence trends, disease form, gender, age, place of residence, and ethnicity distribution

Материал и методы

A retrospective descriptive study based on official health statistics from hematology and oncology centers. All newly diagnosed cases of leukemia in children aged 0–14 years were included. Descriptive statistical methods were used.

Результаты

A total of 541 cases of childhood leukemia were registered. Acute forms dominat-ed (82.4%), with a higher incidence in boys and in the 0–4 years age group. More cases were regis-tered in rural areas. The highest annual number was recorded in 2023 (89 cases). Compared to 2000–2007, the incidence increased significantly

Заключение

Childhood leukemias in Tajikistan are characterized by a steady increase, pre-dominance of acute forms, and distinct age and gender patterns. There is a need to improve early diagnosis, ensure access to specialized care, and implement national monitoring programs

Ключевые слова

leukemia children epidemiology acute leukemia Tajikistan

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Список литературы

  2. Korkina YU. S., Valiev T. T., Varfolomeeva S. R. Klinicheskie i molekulyarno-biologicheskie osobennosti ostryh lejkozov u detej do 1 goda // Onkogematologiya. – 2022. – T. 17, № 2. – S. 23–29. – DOI: 10.17650/1818-8346-2022-17-2-23-29.
  3. Mahacheva F. A., Valiev T. T. Lechenie ostryh mieloidnyh lejkozov u detej: sovremennyj vzglyad na problemu // Onkogematologiya. – 2020. – № 15 (1). – S. 10-27. DOI: 10.17650/1818834620201511027.
  4. Paina O. V., Semenova E. V., Markova I. V. i dr. Sovremennye predstavleniya o terapii ostrogo lejkoza u detej do 1 goda // Rossijskij zhurnal detskoj gematologii i onkologii. – 2019. – T. 6, № 2. – S. 11–19. – DOI: 10.21682/2311-1267-2019-6-2-11-19.
  5. Seregin G. Z., Lifshic A. V., Alekskerova G. A. [i dr.] Vozmozhnosti epigeneticheskoj terapii ostryh mieloidnyh lejkozov u detej // Sovremennaya onkologiya. – 2019. – № 4. – S. 36-39.
  6. Hunger S. P., Lu X., Devidas M. et al. Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the Children’s Oncology Group // J. Clin. Oncol. – 2012. – Vol. 30, No. 14. – P. 1663–1669. – DOI: 10.1200/JCO.2011.37.8018.
  7. Rubnitz J. E., Razzouk B. I., Lensing S. [et al.] Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia // Cancer. – 2007. – Vol. 109, N 1. – P. 157-163. DOI: 10.1002/cncr.22385.
  8. SEER Cancer Statistics Review, 1975-2010 / Eds. Howlader N., Noone A. M., Krapcho M. et al. – Bethesda: National Cancer Institute, 2013. – URL: [https://seer.cancer.gov/archive/csr/1975_2010/](https://seer.cancer.gov/archive/csr/1975_2010/)
  9. Swerdlow S. H., Campo E., Harris N. L. [et al.] WHO classification of tumours of haematopoietic and lymphoid tissues. – Revised 4th edn. IARC: Lyon. – 2017.