Аннотация

Цель
To investigate the characteristics of chronic heart failure (CHF) in combination with atrial fibrillation (AF) depending on left ventricular ejection fraction (LVEF).
Материал и методы
A retrospective cohort study included data from medical records of 650 patients with cardiovascular diseases (CVD) complicated by CHF, hospitalized in the cardiology department of the State Institution «Republican Clinical Cardiology Center» of the Ministry of Health and Social Protection of the Population of the Republic of Tajikistan from 2018 to 2020. Of the total number of patients (n=650), 55.1% (n=358) were men and 44.9% (n=292) were women. An analysis was conducted on the incidence of AF, its association with various types of CHF (with preserved LVEF (CHF-pEF), with mid-range LVEF (CHF-mrEF), and with reduced LVEF (CHF-rEF)), as well as an analysis of concomitant pathology, recurrent hospitalizations, and cardiovascular mortality.
Результаты
AF was identified in 239 (36.8%) patients. AF was most frequently observed in CHF-rEF (43.9%), less frequently in CHF-mrEF (16.7%). In the CHF-pEF group, patients were older, with a higher proportion of women (64.9% in the AF subgroup) compared to the AF groups with CHF-mrEF (42.5%) and AF with CHF-rEF (27.5%). The frequency of T2DM and impaired renal function was comparable in groups with different types of CHF. A statistically significant difference (p<0.001) was found in the frequency of MI in the anamnesis between groups, with the highest frequency (47.6%) in the AF group with CHF-rEF. Recurrent hospitalizations were observed in almost every second patient with AF regardless of the type of CHF. Cardiovascular mortality was highest in the group of patients with AF and CHF-rEF (12.4%).
Заключение
CHF in combination with AF has different characteristics depending on LVEF. Reduced LVEF is an unfavorable prognostic factor in patients with AF, associated with an increased risk of cardiovascular mortality.

Ключевые слова

Chronic Heart Failure (CHF) Atrial Fibrillation (AF) Left Ventricular Ejection Fraction (LVEF).

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